User blog comment:Jimeee/Skyrim 1.9 beta update adds Legendary difficulty and raises level cap (Updated Apr 8th)/@comment-60.229.35.51-20130410022825/@comment-7453433-20130410104805

I think the best way is one handed. as long as your smithing and enchanting is good then the lack of skill in the one handed perk doesnt matter at higher levels as you can counter act this by enchanting your armour with forify one handed. works great against giants and mamoths as long as you have a high armour rating.