User blog comment:Zelron/Kill Everything (Thinking outside the box)/@comment-4057437-20121213193520

Alchemy can also be useful, especially poisons such as Slow and Paralyse. Poisons made by a character with a high Alchemy skill, the right perks and wearing five pieces of enchanted (fortify alchemy), apparal can be quite powerful. Add to that the Sneak perk Poisoned and a high Sneak and  many humanoid foes don't stand a chance.

As for Pickpocket, what about putting an Exploding Spider into an enemy's inventory and having it go off? (It doesn't do anything right now, we tried it.)