User blog comment:Blood Reaper/Todd Howard Hinting at Future DLC's and Patches/@comment-98.221.244.27-20120219195308/@comment-72.230.139.70-20120220031309

I think you should be able to join/destroy (almost) any faction. For example, I don't always want to join the Thieves Guild, and I hate seeing the quest in my menu. It would be rather cool if I could destroy them, once and for all.