Board Thread:Online Discussion/@comment-24380143-20140108000635/@comment-69.35.184.56-20140109191033

If it's like in Skyrim the NPC would probably spawn at the beginning of the quest, or spawning when you enter the area, like it might be with other NPCs in quests that aren't Dark Brotherhood related. Or when others kill named NPCs they respawn when the player leaves the area. There could also be an additional option that doesn't affect the storyline where you can kill other players for money. Another option is killing a number of players along with the occasional NPC after killing players.