User blog comment:Skolu/Challenge: Are you better?/@comment-1992639-20121127120300/@comment-4810762-20121129114634

If you are smart, you can make a incredibly damage health poison, that you can use 4 times. I tryed myself, and Ancient Dragons dont like poisons that damage over 6000. In the alchemy skill tree you shall take the Concentrated Posion perk, then you can use it 2 times. And if you complete A Return To Your Roots, you just need to quicksave before you make the poison. After some time with Sinderions Sependity (I think that is what it is called) you will get 2 poisons. With a good damage bow, and Dark Brotherhood gloves + Deadly Aim you will kick some ass. Ps, you can use poisons against undead.