Board Thread:Lore Discussion/@comment-71.61.178.23-20130722105712/@comment-24489208-20130723213829

When it comes to negative effects:

Sanguine: -10 for each time you cure an achoholic

Sheogorath: -10 for making someone sane (And you missed this, +10 for each time you drive someone mad with a specific class of Illusion spell.)

(That's all I can think of)

And with Jygga, the exact opposite of Sheo. Aka, +10 for making someone sane and -10 for driving someone mad and perhaps -5 for using mix-matched armour instead of matching pieces.