Board Thread:Skyrim/@comment-13670863-20150408221950/@comment-26662848-20150515053633

You have a chance to make a lot of money if you join the Dark Brotherhood. You'd miss the opportunity to complete an entire questline, (The Dark Brotherhood Story) if you destroy them. The quests are also very enjoyable. They mostly involve planned assassinations, not too much combat involved.

But it depends entirely on your preferences.