In 4E 1 she was dispatched to Cylarne to assist the Saints there in taking the holy site from the Dark Seducers; she was placed in command of the Altar of Rapture, and was tasked with finding a way to break through the Mazken defenses.
Her tour in Cylarne would eventually come to an end when the Hero appeared there as an emissary from Sheogorath seeking to re-light the Flame of Agnon.
Sheogorath tasks the Hero with relighting the Great Torch, which has gone out since the Greymarch began. They must go to Cylarne to get the Flame of Agnon in order to relight the torch.
What happened next is unclear, but the Hero allied with either the Aureals or the Mazken ("Dark Seducers") in the last battle over Cylarne. Kaneh either died fighting the Mazken, or sacrificed herself to light the Altar of Despair after the Hero helped her and the Saints take it from the Seducers. Her soul was sent to the Waters of Oblivion, and did not return to the Isles for many years.